In this lesson, Prof. Della Porta - Head of the Leukemia Unit at Humanitas Research Hospital Cancer Center and also Full Professor of Hematology in Humanitas University - guides us through the transformative role of artificial intelligence (AI) in hematology, focusing on diagnostics and therapeutics. We will explore how AI is driving a shift from traditional disease classification systems to those based on genomic information, facilitated by next-generation sequencing (NGS). This transition enables more targeted, personalized therapies and treatment strategies for patients with hematological diseases, such as leukemia. We will also cover the concepts of subphenotyping and clustering, showing how AI helps identify specific biological subtypes of diseases, ultimately improving patient prognosis and treatment outcomes.
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